A loxP site and an frt-flanked neomycin selection cassette was inserted between exons 2 and 3, and a second loxP site was inserted between exons 6 and 7. The neomycin selection cassette was removed via Flp-mediated recombination. (J:232731)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count