RMCE introduced into the 3' UTR the targeting construct Sox2-frt-invCAG that contains and inverted CAG promoter, the Sox2 gene, an IRES sequence and a CFP reporter gene. Cre-mediated recombination is required to achieve expression. (J:236715)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count