A Neomycin resistance gene cassette (flanked by FRT sites) was inserted between exons 2 and 3. The first and second loxP sites were inserted upstream of the neomycin selection cassette and downstream of exon 5, respectively. The neomycin selection cassete was removed via flp-mediated recombination. (J:260669)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count