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The transgene is comprised of an 8.0 kb genomic fragment comprising the sequences between 5.6 kb upstream of the Olfr73 start codon, and the PvuII site in the 3 untranslated region. A SacII-NotI site was engineered downstream of the Olfr73 stop codon, into which a IRES-gapEGFP was inserted, which encodes an internal ribosome entry site (IRES) and a fusion protein consisting of the N-terminal 20 amino acids of Gap43 and EGFP. Three lines of mice expressing the transgene in different patterns were generated, TgA, TgB and TgC. (J:117260)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
