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Exon 18 was replaced with a modified on in which nucleotide substitutions result in the amino acid substitution of alanine for serine at position 749 (S749A). This mutation is predicted to cause the loss of enzyme activity. Flp-mediated recombination removed an FRT-flanked neomycin resistance cassette. (J:251322)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
