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EN
This targeted knockout-first reporter allele with conditional potential (conditional-ready) was generated by electroporating ES cells with the EUCOMM vector PG00143_Z_7_G04 to insert a DNA sequence containing a FRT site; a lacZ cassette containing the En2 splice acceptor and a polyadenylation signal (p[A]); a loxP site; a promoter-driven neomycin resistance cassette with a p[A]; a second FRT site; and a second loxP site into the second intron and a third loxP site into the fourth intron of the mouse gene. (J:94077)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
