CRISPR/Cas9 methodologies were used to delete 61 bp of mouse gene Car10 (including the last 32 bp of exon 2). The guide RNA (gRNA) sequences for the Car10 mutation were: TGAAGGCTGGTGGGCATACAAGG and CCAGGGAAGCTTTGTTCCAGGTA. The exon 2 sequence deletion involves chr11:93185125-93185185. (J:101977)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(C57BL/6J x SJL/J)F1/J
Endonuclease-mediated
Intragenic deletion
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1
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Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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