This allele from project TCPR0451 was generated at The Centre for Phenogenomics by injecting Cas9 mRNA and four guide RNAs with spacer sequences of AGAATCGAAGCGTCCACAGC and TACATCTACCCTCGTCCTGG targeting the 5' side and TCGGGTGTTAGAGCCTTGGC and GCCTTAGGCCCCCTCTAGAA targeting the 3' side of exon ENSMUSE00000346888 (exon 1). This resulted in a 679 bp deletion and 2 bp insertion of Chr11 from 76679972 to 76680650, and a 15 bp deletion and 7 bp insertion of Chr11 from 76680678 to 76680692. (GRCm38). (J:237616)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6NCrl
Endonuclease-mediated
Intragenic deletion
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1
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Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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