This allele from project TCPR0651 was generated at The Centre for Phenogenomics by injecting Cas9 mRNA and four guide RNAs with spacer sequences of AACTGCCACAAGTTGCCTTC and CACATACCGTAATAACTAGC targeting the 5' side and GGAAACTGCAGAGTACGGT and ACAAAGGCCGAGCTATCTTC targeting the 3' side of a critical region. This resulted in a 3,481-bp deletion of Chr19 from 3276537 to 3280017 with insertion of insTTTC. (GRCm38). (J:237616)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6NCrl
Endonuclease-mediated
Intragenic deletion
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1
10
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Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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