This allele from project TCPR0785 was generated at The Centre for Phenogenomics by electroporating Cas9 ribonucleoprotein complexes with single guide RNAs having spacer sequences of TCCAAGCCTAAGAACACACT and GGGAACAAGGATAGACTTGC targeting the 5' side and GGCTTTCGCTTAGCGCTCCT and AGTCTGCGTCACTAAGTCAC targeting the 3' side of exon ENSMUSE00001152754. This resulted in a 1572-bp deletion Chr11: 33492917 to 33494488 gRNA_U5 to _D3 (GRCm38). (J:237616)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6NCrl
Endonuclease-mediated
Intragenic deletion
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1
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Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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