This allele from project TCPR0864 was generated at The Centre for Phenogenomics by electroporating Cas9 ribonucleoprotein complexes with single guide RNAs having spacer sequences of GCAGTTGGATTAAGTAGCAC and TCTTTGGTCTAGCGAGATTG targeting the 5' side and TCCTAGAGCTATGGACATGG and GTGCATACCTCTAGCAGCCC targeting the 3' side of a critical region. This resulted in a 12-bp deletion Chr6:28519921 to 28519932; 325-bp deletion Chr6:28520030 to 28520354; 11- bp deletion Chr6:28520400 to 28520410 (GRCm38). (J:237616)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6NCrl
Endonuclease-mediated
Intragenic deletion
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1
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Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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