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This allele from project TCPR0683 was generated at The Centre for Phenogenomics by injecting Cas9 mRNA and three guide RNAs with spacer sequences of GCAGCTAACATTCGTTCTTC and CTTTACTGTAGGGATCATAC targeting the 5' side and ACAACGCACACCCCACCGAA targeting the 3' side of exon ENSMUSE00000701722 resulting in a 685-bp deletion of Chr9 from 35561247 to 35561931 (gRNA_U3 to gRNA_D). This mutation is predicted to cause a frameshift with the amino acid changes after residue 63 and early truncation 38 amino acids later (c.188_872del, p.D63Gfs*40). (GRCm38). (J:237616)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
