This allele from project TCPR0780 was generated at The Centre for Phenogenomics by electroporating Cas9 ribonucleoprotein complexes with single guide RNAs having spacer sequences of TGGCTATAGTATCGCTGTGT and GGTTGAGCTCCTAACAAAAT targeting the 5' side and ATGTAGCCCAAGACTTGTAC and GCTACAACTGGTTACATTCA targeting the 3' side of exon ENSMUSE00000444358 and ENSMUSE00000444356. This resuled in a 1431-bp deletion of Chr6 from 53952328 to 53953758 with an insertion of ACCAGT (GRCm38). (J:237616)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6NCrl
Endonuclease-mediated
Insertion
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1
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Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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