This allele from project TCPR0672 was generated at The Centre for Phenogenomics by injecting Cas9 mRNA and four guide RNAs with spacer sequences of GTGCATGCCAGCACTCCCTA and ACAGTTCAACAGCTTCGCCC targeting the 5' side and ATATGGGCTAAATGTGCCTC and CTCAGAAGACCTTTATTAGG targeting the 3' side of exon ENSMUSE00000237794. This resulted in a 435-bp deletion of Chr19 from 7614350 to 7614784, a 6-bp deletion of Chr19 from 7614245 to 7614250, and a 8-bp deletion of Chr19:7614932 to 7614939_insCTCTCTC. (GRCm38). (J:237616)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6NCrl
Endonuclease-mediated
Intragenic deletion
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1
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Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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