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EN
This allele from project TCPR1020 was generated at The Centre for Phenogenomics by electroporating Cas9 ribonucleoprotein complexes with single guide RNAs having spacer sequences of GGAATGTGCGGAATTCCCTG targeting the 5' side and AGTTATGCAAACCTATGACC targeting the 3' side of a critical exon. This resulted in a 511-bp deletion Chr14:61604671 to 61605181; p.L46Tfs*45 resulting in a frameshift mutation in all annotated full length protein-coding transcripts (GRCm38). (J:237616)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
