This allele from project TCPR0944 was generated at The Centre for Phenogenomics by electroporating Cas9 ribonucleoprotein complexes with four single guide RNAs having spacer sequences of GACCTTAGTACTTGTTTAAA and CACCCATGTTAAACTAAAAG targeting the 5' side and CATGCGCAGATCCCGTTAAG and TAGTTAGGGAGCGCGAGTGA targeting the 3' side of exon ENSMUSE00001354960, ENSMUSE00001356626, ENSMUSE00001346722, ENSMUSE00000175327 and ENSMUSE00000175325 resulting a 2,421-bp deletion Chr3:132671874 to 132674294 (GRCm38). (J:237616)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6NCrl
Endonuclease-mediated
Intragenic deletion
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1
3
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Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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