A FRT site, GFP, loxP site, neomycin resistance cassette, FRT and a loxP site were inserted upstream of exon 3 and a third loxP site was inserted downstream of exon 5. Flp-mediated recombination removed the neomycin and GFP. Cre-mediated recombination removed exons 3-5. (J:261409)
Basic Information
129S6/SvEvTac or C57BL/6J
Insertion, Intragenic deletion
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count