A loxP site and FRT-flanked neomycin selection cassette were inserted upstream of exon 2 and a second loxP site was inserted downstream of exon 6. Flp-mediated recombination removed the selection cassette leaving exons 2-6 floxed. (J:261336)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count