A loxP site was inserted upstream of exon 14 and a FRT-flanked neomycin selection cassette and a second loxP site were inserted downstream of exon 14. Flp-mediated recombination removed the selection cassette, leaving exon 14, encoding part of the beta-propeller domain, floxed. (J:234556)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count