Exons 3 to 7 were flanked by loxP sites and a FRT-flanked neomycin phosphotransferase cassette was inserted after exon 7 and before the second loxP site. Flp-mediated recombination removed the selection cassette, leaving exons 3-7 floxed. (J:241676)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count