A loxP site was inserted upstream of exon 4 and a FRT-flanked PGK-neo cassette and a second loxP site were inserted downstream of exon 4. FLP-mediated recombination removed the selection cassette, leaving exon 4 floxed. (J:246431)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count