Exon 1 was flanked by loxP sites. An FRT site flanked neomycin resistance gene cassette was inserted into intron 1. The neo cassette was removed through subsequent flp-mediated recombination. This creates a conditional-ready allele with exon 1 floxed. (J:253309)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count