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CRISPR/Cas9 genome editing technology was used to generate a 191bp deletion that included exon 8 of the gene. This allele from IMPC was generated at Welcome Trust Sanger Institute by injecting CAS9 RNA and 4 guide sequences CCATGTATGTAGGCAAACTTGGC, TGTTAATGTCTTCTGCTATCAGG, CAACAGGGCAGGTAAGACGAAGG, TAAGAGTATTTCAGTGGACTAGG. (J:237616, J:332580)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
