Exon 3 was flanked by loxP sites. The puromycin resistance cassette was introduced as a selection marker and removed by mating of heterozygous mice with transgenic mice ubiquitously expressing Flp-recombinase. (J:259702)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count