The allele was generated to insert loxP sites flanking exon 2 of the Bace1 gene. The neo cassette flanked with FLP recombinase target (FRT) sites was removed from founder mice by crossing with crossed with the FLP deleter strain. (J:259749)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count