LoxP sites were inserted to flank exons 35. An frt-flanked neomycin selection cassette was removed by crossing chimeric mice with beta-actin-FLPe transgenic mice (J:259797)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count