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An 8.4-kb fragment of the mouse alpha-gustducin gene (GUS8.4 promoter) that drives taste receptor cell-specific expression was cloned 5 to the rat mutated G352P-alpha-gustducin cDNA. The mutation is a single glycine to proline substitution at position 352 near its C terminus (G352P). Three lines of mice (nos. 81, 82, and 89) were generated. Line 82 was chosen for further analysis because the pattern of alpha-gustducin expression matched or exceeded that of WT. (J:128673)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
