A loxP aite was inserted 5' to exon 1 and a loxP-flanked neomycin selection cassette was inserted 3' to exon 1. Cre-mediated recombination removed both exon 1 and the loxP-flanked neomycin selection cassette. (J:259087)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count