A loxP site was inserted upstream of Mir23a and an FRT-flanked pgk-neo cassette, duplicate copy of Mir27a and loxP site were inserted downstream of Mir23a. The extra copy of Mir27a ensures that the full flanking region of the microRNA is maintained after Cre-mediated recombination. (J:258662)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6
Targeted
Insertion
--
--
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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