A Y14F mutation was introduced in exon 2 and a floxed neo cassette was inserted in intron 1 via homologous recombination. In the absence of Cre-mediated recombination the mutant protein is not expressed. (J:232807)
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A Y14F mutation was introduced in exon 2 and a floxed neo cassette was inserted in intron 1 via homologous recombination. In the absence of Cre-mediated recombination the mutant protein is not expressed. (J:232807)