Log In|Sign Up
EN
Exons 4-6 were replaced with a loxP site flanked neomycin selection cassette. This is predicted to cause a a premature stop codon due to a frame shift, resulting in a truncated peptide that would lack the SAM domain. Absence of mRNA and protein expression from this allele in homozygous mice was confirmed by RT-PCR and Western blot, respectively. (J:253631)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
