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CRISPR mutagenesis introduced a 1644bp deletion from the middle of exon 3 to the middle of exon 4, resulting in a frame-shift with a deletion of 248 nucleotides in the mRNA product and the introduction of a premature stop codon. Western blot analysis of tissue lysates from embryos showed that the encoded protein is absent in the homozygous mutant samples. (J:242905)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
