The targeting construct introduced into the loci a CAG promoter, floxed STOP cassette, a non-binding S1pr1 with a R120A amino-acid substitution fused to tag RFP (tRFP), a P2A ribosomal skip sequence and S1pr1 fused to EGFP. (J:234057)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count