Exon 3 was flanked with loxP sites and an adjacent frt-flanked neomycin selection cassette was removed via FLP-mediated recombination. Exon 2 contains the sequences encoding the adenosine triphosphate binding site; deletion results in a frameshift and the introduction of a premature stop codon. (J:248415)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count