A targeting vector was designed to insert a cre/ERT2 cassette followed by an FRT-flanked neo cassette into the ATG codon of mouse Zfyve27 gene via homologous recombination in ES cells. The resulting chimeric animals were bred to germline-active ACTB-Flpe deleter transgenic mice to delete the FRT5-flanked neo cassette. (J:259138)
Basic Information
(C57BL/6J x 129S6/SvEvTac)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count