A targeting vector was designed to insert a cre/ERT2 cassette followed by an FRT-flanked neo cassette into the ATG codon of mouse Zfyve27 gene via homologous recombination in ES cells. The resulting chimeric animals were bred to germline-active ACTB-Flpe deleter transgenic mice to delete the FRT5-flanked neo cassette. (J:259138)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(C57BL/6J x 129S6/SvEvTac)F1
Targeted
Insertion
--
1
1
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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