The following sequences were inserted between Igkj segments and the Igk-Eik super-enhancer: murine Igh core switch region mu, human IGK-EIK super-enhancer, human IGK constant region, Igkv 4-63 promoter sequence and 1st exon with a STOP sequence, murine Igh core switch region gamma3, and a loxP site flanked neomycin resistance gene cassette. (J:224373)
Basic Information
Insertion, Intragenic deletion
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count