A 1.6-kb DNA fragment containing exon 2 was flanked with loxP sites, with an frt-flanked neomycin resistance cassette inserted downstream of exon 2. The neomycin selection cassette was removed by crossing to Flp mice. (J:236134)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count