The human GFAP promoter drives expression of this transgene that includes a mutagenized green fluorescent calcium indicator (GCaMP3), woodchuck hepatitis virus posttranscriptional regulatory element (WPRE), and SV40 polyadenylation sequence. GCaMP consists of a circularly permutated green fluorescent protein (cpGFP), the calcium-binding protein calmodulin (CaM), and CaM-interacting M13 peptide. (J:258504)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count