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A loxP site was inserted at position 47703, a mutated exon 15 with an A947T mutation (GCA to ACA) was introduced and an FRT flanked neo cassette and loxP site were inserted at position 50710 via homologous recombination. This mutation mimics the human type 1 diabetes risk allele. (J:257959)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
