A loxP site and FRT flanked selection cassette were inserted upstream of exon 3 and an F3 site and loxP site were inserted downstream of exon 3 via homologous recombination. Flp meditated recombination removed the selection cassette. (J:147112)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count