A construct containing Hoxb8 upstream sequences, a FlipO recombinase cassette, and a bovine poly(A) sequence inserted in-frame downstream of the Hoxb8 ATG site was used. Fertilized early-stage C57BL/6J oocytes were injected with the linearized construct, and two founders were obtained. Founders were mated to generate transgenic lines, one of them, F11, exhibited the expected expression pattern of Hoxb8 at P0. (J:82809)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6J
--
Insertion
--
--
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
Wechat
Comparison
Al agent
Tutorials
Back to top