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A PGK-beta-geo (beta-galactosidase-neomycin fusion gene) selection cassette was inserted into exon 4, disrupting the second ATG that gives rise to the short isoform. RT-PCR confirmed disrupted mRNA expression of the long and short forms and low expression of a miniform spanning exons 1, 6, and 7 (354 bp), which can produce a peptide from an alternative start codon in exon 7. (J:233160)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
