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The transgene contains the EGFP (enhanced green fluorescent protein) gene under the control of a promoter consisting of six consensus lymphoid enhancer binding factor 1/transcription factor 3 (LEF/TCF)-binding motifs upstream of a minimal TK promoter, followed by a polyadenylation signal. The entire construct was flanked by two copies of insulator core elements to minimize positional effects imposed by chromosome structure. This construct is responsive to canonical Wnt/beta-catenin signal transduction. (J:258203)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
