A loxP site and F3 flanked puro cassette were inserted upstream of exon 3 and a loxP site was inserted downstream of exon 3 via homologous recombination. Flp-mediated recombination removed the puro cassette. (J:217486, J:258184)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count