A loxP was inserted upstream of exon 5 and an FRT flanked neomycin resistance gene cassette with a 3' loxP site was inserted downstream of exon 5. The neo cassette was removed by crossing with FLPe mice (C57BL/6-Tg(CAG-FLPe)36Ito). (J:198470)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Targeted
Insertion
--
1
3
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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