The transgenic construct contains a 5.4-kb murine Myh6 promoter directing expression of the mouse hydroxysteroid 11-beta dehydrogenase 2 (Hsd11b2) cDNA, followed by human growth hormone and polyadenylation cassette. Founder line 326 has 29 copies of the transgene. (J:258076)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count