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A pair of loxP sites with a loxP-flanked neo gene cassette flanking alternatively spliced exons 11 to 13 was generated. Transient Cre expression in ES cells resulted in the deletion of exons 11-13 and the lack of expression of the long isoform of the Chd8 gene. The short isoform is expressed. (J:235128)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
