CRISPR/Cas9 technology inserted loxP sites flanking exon 4a and a FRT-flanked neomycin selection cassette downstream of the floxed exon. Flp-mediated recombination deleted the neomycin cassette. (J:257982)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count