A FRT-flanked PGK-neomycin cassette and a loxP site were inserted upstream of exon 3 and a second loxP site downstream of exon 4. Flp-mediated recombination removed the selection cassette, leaving exons 3-4 floxed. (J:257972)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count