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The human keratin 14 (KRT14) promoter drives the expression of a chimeric gene consisting of both cDNA and genomic sequences encoding latent membrane protein 2A (LMP2A) of Epsterin Barr Virus (EBV). Epithelial expression of LMP2A was demonstrated by immunoblot analysis of protein from dorsal skin of mice of transgenic line 102. Indirect immunofluorescence imaging showed expression of LMP2A and of endogenous keratin 14 to be localized to the basal level of the developing epidermis in both tail skin and tongue epithelia. (J:131112)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
